Impermanence gets mentioned a lot around Buddhists. How does impermanence show up in my life?

When we talk about impermanence, if we look at our lives, from childhood so many changes have taken place, in our body, in our mind. So life contains many things that have changed in our lives.

What we mean by impermanence is that things keep on changing, that things never stay the same, that is what is meant by impermanence. 

HH, 17^th Karmapa
Ogyen Trinley Dorje

From Kamashila
Short-Ngon-dro teaching
Germany, 2014